PROTACs: A Paradigm Shift in Drug Discovery – Module 3

Program Overview

Navigating the Frontier of Hematologic Malignancy Therapies (3 of 5 Modules)

This activity provides an overview of emerging data in the development of proteolysis targeting chimeras (PROTACs) that harness intracellular E3-ubiquitin ligases for the treatment of hematologic malignancies.

CE Credit Expired
Expires: March 12, 2024

Target Audience

Hematologists, oncologists, and other healthcare professionals involved in the diagnosis and treatment of patients with blood cancers.

Educational Objectives

Upon completion of this activity, participants should be better able to:

  • Describe emerging proteolysis targeting chimeras (PROTACs) under investigation for the treatment of hematologic malignancies

Activity Faculty

Donovan, Katherine-Faculty Headshot-135x135

Katherine Donovan, PhD

Lead Scientist, Department of Cancer Biology
Dana-Farber Cancer Institute
Harvard Medical School
Boston, MA

Provider Statement

This activity is jointly provided by The Leukemia & Lymphoma Society and RMEI Medical Education, LLC.

Supporter Statement

The educational portion of this program is supported by an independent educational grant from AstraZeneca Pharmaceuticals LP. Additional funding provided by The Leukemia & Lymphoma Society.

Disclosure of Financial Relationships 

RMEI Medical Education, LLC (RMEI) requires instructors, planners, managers, and others in control of educational content to disclose all their financial relationships with ineligible companies over the previous 24 months.  All identified financial relationships are thoroughly vetted and mitigated according to RMEI policy. 

Faculty 

Katherine Donovan, PhD, has relevant financial relationships with Kronos Bio, Neomorph Inc. (Consultant); Neomorph Inc. (Speaker/Speaker’s Bureau).

All of the relevant financial relationships listed for this individual have been mitigated according to RMEI policies. 

Planners and Managers

RMEI Medical Education, LLC planners and managers have no relevant financial relationship(s) with ineligible companies to disclose.

Joint Accreditation Statement 

In support of improving patient care, this activity has been planned and implemented by RMEI Medical Education, LLC and The Leukemia & Lymphoma Society. RMEI Medical Education, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

 

Credit Designation

Physician Credit Designation 
RMEI Medical Education, LLC designates this enduring material for a maximum of 0.5 AMA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Instructions for Participation and Credit 

In order to receive credit, users must: 

  • Read the learning objective and faculty disclosures 
  • Participate in the activity 
  • Complete the activity evaluation

 
There is no fee to participate.  

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. 

Disclaimer Statement

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. 

Copyright Statement

© Copyright 2023. All rights reserved. Developed and managed by RMEI Medical Education, LLC. Laurel Office Plaza | 101 Laurel Road, Suite 200 | Voorhees, NJ 08043 | www.RMEI.com | (866) 770-RMEI

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