Medical News, Journals & Upcoming Events
Latest Hematology / Oncology Articles
- Continuous or Fixed-Duration Maintenance Therapy in Multiple Myeloma July 16, 2026Among patients with multiple myeloma, 7-year overall survival with 2 years of lenalidomide therapy was similar to that with indefinite therapy. Adverse events and second cancers were more common with indefinite therapy.Shaji Kumar, Susanna Jacobus, Adam Cohen, Matthias Weiss, Natalie Callander, Avina Singh, Terri Parker, Michael Green, Raymond Thertulien, Benjamin Parsons, Pankaj Kumar, Prashant Kapoor, Aaron Rosenberg, Elie Dib, Daniel Almquist, Jeffrey Zonder, Edward Faber, Zihan Wei, Kenneth Anderson, Sagar Lonial, Paul Richardson, Robert Orlowski, Lynne Wagner, S. Vincent Rajkumar
- Time to Stop? Rethinking the Duration of Maintenance Treatment in Multiple Myeloma July 16, 2026Multiple myeloma has undergone a therapeutic revolution at a pace nearly unmatched in oncology. Yet amid these advances, a key assumption in multiple myeloma therapy persists: more and longer treatment is better. The trial by Kumar and colleagues (ENDURANCE), reported in this issue of the Journal,1 ...Hira Mian, Luciano J. Costa
- Platelet-Activating Anti–Platelet Factor 4 Disorders July 13, 2026This review summarizes platelet-activating anti–platelet factor 4 disorders, including heparin-induced thrombocytopenia and related syndromes, highlighting diagnosis, antibody mechanisms, and treatment strategies.Theodore E. Warkentin, Andreas Greinacher
Latest Allergy & Immunology Articles
- Targeted Degradation of NETs in Lupus with DNASE1L3 Deficiency July 16, 2026Recombinant DNASE1L3 therapy reduced symptoms in a patient with severe lupus with DNASE1L3 deficiency. Antidrug antibodies caused effects to wane, but findings support NET-targeted therapy as a nonimmunosuppressive approach.Tadej Avčin, Andreas Reiff, Maša Bizjak, Barbara Jenko Bizjan, Tina Vesel Tajnšek, Maruša Debeljak, Tyler Artner, Bernd Jilma, Christian Lood, Abdul Hakkim, Tobias A. Fuchs
- Case 20-2026: A 38-Year-Old Man with Abdominal Pain July 16, 2026A 38-year-old man was evaluated at the hospital because of postprandial abdominal pain. Six weeks earlier, a diarrheal illness had developed while he was working in Madagascar. A diagnosis was made.Aima A. Ahonkhai, Howard M. Heller, Sarah M. Schrader
- Efficacy and Safety of Obinutuzumab in Active Systemic Lupus Erythematosus July 16, 2026In patients with SLE without advanced lupus nephritis, obinutuzumab plus standard therapy was superior to placebo plus standard therapy in conferring and sustaining a clinically meaningful reduction in disease activity over 52 weeks.Richard A. Furie, Maria Dall’Era, Edward M. Vital, Jay P. Garg, Fedra Irazoque Palazuelos, Adolfina E. Zuta Santillán, Jorge Ravelo-Hernández, Mittermayer B. Santiago, Beatriz Zazueta Montiel, Stella Botha, Piotr Leszczyński, Viviane Angelina de Souza, Sandra A. Sicsik, Luis Bellatin, Asokan Naidoo, Zahir Amoura, Maria Antonietta D’Agostino, Sunil Kumar, Biruh Workeneh, Julie Rae, Huiyan A. Mao, Felix Erblang, Oliver Meier, Justine C. Maller, Anca D. Askanase, the ALLEGORY Trial Investigators*
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