Dermatology Articles

• Ianalumab in Sjögren’s Disease — A First Step October 22, 2026
  Sjögren’s disease has long frustrated clinicians, trialists, and — most important — patients for whom effective treatments remain elusive. Glandular dysfunction causes dryness; fatigue and pain add substantially to daily burden; and systemic manifestations can affect major organs. These dimensions of disease do not necessarily track together. Management of dryness...
  Simone Negrini
• Ianalumab for the Treatment of Patients with Sjögren’s Disease October 22, 2026
  In two trials involving patients with active Sjögren’s disease, decreases in disease activity at 48 weeks were greater with monthly ianalumab than with placebo, but differences in response rates and symptom scores were not significant.
  Xavier Mariette, Thomas Grader-Beck, Stephanie Finzel, Elena Schiopu, Athena Papas, Valerie Devauchelle-Pensec, Monika Sopala, Xiaofeng Zeng, Ghaith Noaiseh, Tsutomu Takeuchi, Uma Kumar, Josef Hermann, Hiroki Ozawa, Robert Fox, Susan Zong, Deepak Narayanswamy, Xiaomei Li, Wen-Lin Luo, Janice Woznicki, Laurie Debonnett, Xuan Zhu, Linchen He, Franziska Matzkies, Angelika Jahreis, Devendra Kumar Jain, Brian Porter, Carol Lau, Thomas Dörner, Sara S. McCoy, Simon J. Bowman, Wolfgang Hueber, the NEPTUNUS-1 and NEPTUNUS-2 Investigators*
• Alkaptonuria October 15, 2026
  A 64-year-old woman presented with progressive stooped posture, low back pain, and difficulty walking. Examination showed black scleral pigmentation, and a urine sample turned black after standing overnight.
  Prasanta Padhan, Pratima Singh