Genetic analyses of three families with disabling pansclerotic morphea uncovered a cause of the disease, providing insight into the molecular pathology of the disease and leading to an experimental, targeted treatment.
Hratch Baghdassarian, Sarah A. Blackstone, Owen S. Clay, Rachael Philips, Brynja Matthiasardottir, Michele Nehrebecky, Vivian K. Hua, Rachael McVicar, Yang Liu, Suzanne M. Tucker, Davide Randazzo, Natalie Deuitch, Sofia Rosenzweig, Adam Mark, Roman Sasik, Kathleen M. Fisch, Pallavi Pimpale Chavan, Elif Eren, Norman R. Watts, Chi A. Ma, Massimo Gadina, Daniella M. Schwartz, Anwesha Sanyal, Giffin Werner, David R. Murdock, Nobuyuki Horita, Shimul Chowdhury, David Dimmock, Kristen Jepsen, Elaine F. Remmers, Raphaela Goldbach-Mansky, William A. Gahl, John J. O’Shea, Joshua D. Milner, Nathan E. Lewis, Johanna Chang, Daniel L. Kastner, Kathryn Torok, Hirotsugu Oda, Christopher D. Putnam, Lori Broderick
A 44-year-old man with HIV infection presented with a 1-month history of fevers and skin lesions. Examination was notable for blackish-brown lamellated plaques on his limbs and scalp that resembled oyster shells.
A 55-year-old man in the ICU had a sudden-onset vesicular rash appear across his trunk and arms. On examination, he was febrile and had clear vesicles resembling water droplets across his torso (shown in a video).
Tal Goldberger, Gil Armoni-Weiss
RMEI LIGHTNING TALKS
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4 Years, 16 Live & Online Activities, 6000+ Clinicians: What we've learned so far
RMEI has released pairings of live and online programs approximately twice per year since 2016 grouped into “phases” which share clinical areas of focus and are based on findings from the previous phase of education. In total, 16 activities have launched to date with 4 activities currently live. The purpose of this analysis is to better understand the impact of multi-year iterative education on a clinical audience. Presented at: Society for Academic CME (SACME), virtual, February 2021; Accreditation Council for Continuing Medical Education (ACCME), virtual, April 2021.
Allergy & Immunology
2021
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Effectiveness of 5-year IBD Provider Online Educational Intervention Program
There is considerable practice variability among providers caring for inflammatory bowel disease (IBD) patients. Limited data exists on the effectiveness of educational interventions targeting IBD providers to address these gaps. We report outcomes for a 5-year provider education training program which culminated in an enduring online education resource and clinical decision support tool.