Latest Hematology / Oncology Articles

• Anticoagulation with Edoxaban in Patients with Atrial High-Rate Episodes September 28, 2023
  In patients with atrial high-rate episodes, edoxaban did not significantly reduce the incidence of stroke and cardiovascular outcomes as compared with placebo, but it led to a higher incidence of bleeding.
  Paulus Kirchhof, Tobias Toennis, Andreas Goette, A. John Camm, Hans Christoph Diener, Nina Becher, Emanuele Bertaglia, Carina Blomstrom Lundqvist, Martin Borlich, Axel Brandes, Nuno Cabanelas, Melanie Calvert, Gregory Chlouverakis, Gheorghe-Andrei Dan, Joris R. de Groot, Wolfgang Dichtl, Borys Kravchuk, Andrzej Lubiński, Eloi Marijon, Béla Merkely, Lluís Mont, Ann-Kathrin Ozga, Kim Rajappan, Andrea Sarkozy, Daniel Scherr, Rafał Sznajder, Vasil Velchev, Dan Wichterle, Susanne Sehner, Emmanuel Simantirakis, Gregory Y.H. Lip, Panos Vardas, Ulrich Schotten, Antonia Zapf, the NOAH-AFNET 6 Investigators
• Dabrafenib plus Trametinib in Pediatric Glioma with BRAF V600 Mutations September 21, 2023
  The use of dabrafenib plus trametinib in pediatric low-grade glioma with BRAF V600 mutations led to longer progression-free survival and fewer grade 3 adverse events than standard chemotherapy.
  Eric Bouffet, Jordan R. Hansford, Maria Luisa Garrè, Junichi Hara, Ashley Plant-Fox, Isabelle Aerts, Franco Locatelli, Jasper van der Lugt, Ludmila Papusha, Felix Sahm, Uri Tabori, Kenneth J. Cohen, Roger J. Packer, Olaf Witt, Larissa Sandalic, Ana Bento Pereira da Silva, Mark Russo, Darren R. Hargrave
• A Holy Grail — The Prediction of Protein Structure September 21, 2023
  The 2023 Lasker Award for Basic Medical Research underscores the value of an AI system that predicts the three-dimensional structure of proteins from the one-dimensional sequence of their amino acids.
  Russ B. Altman