Acute graft-versus-host disease (aGvHD) is a common complication of allogenic hematopoietic stem cell transplant (allo-HSCT). Corticosteroids, usually at high doses, comprise the mainstay of first-line treatment for most patients, but can often be intolerable due to adverse events and the development of steroid-dependent disease. In this activity, an interprofessional expert panel discusses a physician-submitted case of a 45-year-old man who developed steroid-dependent aGvHD after undergoing an allo-HSCT for high-risk acute myelogenous leukemia (AML). The panel will provide insight and input from a medical, pharmacy, and PA perspective.
Upon completion of this activity, participants should be better able to:
Associate Professor, Pediatrics and Hematology/Oncology
Ingram Professorship, Pediatric Oncology, Department of Pediatrics
Medical Director, Pediatric Stem Cell Transplantation Program
Vanderbilt University Medical Center
Nashville, TN
Clinical Pharmacist Specialist, Stem Cell Transplant & Cellular Therapy
Vanderbilt University Medical Center
Nashville, TN
Associate Director, Advanced Practice Providers – BMT & Immunotherapy
Fred Hutchinson Cancer Center
Teaching Associate, UW Medicine
University of Washington
Seattle, WA
RMEI Medical Education, LLC (RMEI) requires instructors, planners, managers, and others in control of educational content to disclose all their financial relationships with ineligible companies over the previous 24 months. All identified financial relationships are thoroughly vetted and mitigated according to RMEI policy.
Katie S. Gatwood, PharmD, BCOP, has relevant financial relationship(s) with BiolineRx, Jazz Pharmaceuticals, Kite Pharma, Sanofi (Speaker).
Carrie L. Kitko, MD, has relevant financial relationship(s) with Horizon Therapeutics, Incyte (Advisor).
Christine Yennaco, PA-C, MPH, MCHS, has no relevant financial relationship(s) with ineligible companies to disclose.
All of the relevant financial relationships listed for these individuals have been mitigated according to RMEI policies.
In support of improving patient care, RMEI Medical Education, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Physician Continuing Medical Education
RMEI Medical Education, LLC designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Continuing Pharmacy Education
RMEI Medical Education, LLC designates this continuing education activity for 0.25 contact hour(s) (0.025 CEUs) of the Accreditation Council for Pharmacy Education.
Universal Activity Number – JA4008290-0000-24-009-H01-P
Type of Activity: Knowledge
Continuing Nursing Education
The maximum number of hours awarded for this Continuing Nursing Education activity is 0.25 contact hour(s).
This activity was planned by and for the healthcare team, and learners will receive 0.25 Interprofessional Continuing Education (IPCE) credit(s) for learning and change.
To receive credit, participants must review the activity content and successfully complete both the post-test and evaluation. A statement of credit will be available to print immediately. You must score 100% or higher on the post-test to receive credit for this activity. If you have questions about this activity, please contact RMEI at [email protected].
Users must:
There is no fee to participate.
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This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
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