A Balancing Act: Safety and Success in CMV Management for HCT Patients: A Clinical Forum®

Program Overview

Cytomegalovirus (CMV) is a serious pathogen that leads to considerable illness and death in hematopoietic cell transplant (HCT) patients. The landscape for CMV prevention and treatment in this vulnerable population continues to evolve, with newer antiviral therapies offering efficacy and minimal side effects.

Optimal CMV management should include an individualized approach based on current guidelines, transplant conditioning regimens, treatment toxicities, and potential CMV drug resistance. Join our distinguished panel as they review state-of-the-art therapeutic considerations for managing CMV in HCT patients, including insights on a challenging clinical case from their practice.

Credit Expired

Target Audience

Hematologists/oncologists, transplantation, internal medicine, and infectious disease clinicians

Educational Objectives

Upon completion of this activity, participants should be better able to:

  • Select evidence-based treatments for hematopoietic cell transplant (HCT) patients with cytomegalovirus (CMV) considering newer antiviral medications and guideline recommendations
  • Identify critical limitations to conventional CMV therapies, including side-effect toxicities, that often result in suboptimal outcomes
  • Formulate individualized plans for monitoring and treating HCT patients with CMV, including those with refractory or drug-resistant disease

Activity Faculty

Genovefa Papanicolaou, MD (Chair)

Genovefa Papanicolaou, MD

Director, Infectious Disease Service
Memorial Sloan Kettering Cancer Center
Professor, Medicine
Weill Cornell Medical College, Cornell University
New York, NY

Chemaly 500x500

Roy F. Chemaly, MD, MPH, FACP, FIDSA, CMQ

Professor and Chair
G. P. Bodey, Sr. Distinguished Professorship, Infectious Diseases
Director, Clinical Virology Research
Department of ID/IC/EH
UT MD Anderson Cancer Center
Houston, TX

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