Antibody-Mediated Rejection: Addressing the Underlying Issues for Improved Patient Outcomes

Program Overview

Join us on Wednesday, July 15 for a live web-based CME/MOC symposium as Drs. Robert Montgomery, Stanley Jordan, and Arjang Djamali discuss the pathophysiology of antibody-mediated rejection (AMR), efficacy and safety data supporting existing and emerging treatment options, and appropriate treatments for patients with AMR to improve allograft survival. This expert panel will also be joined by an experienced solid organ transplant (SOT) patient with AMR who shares his transplant journey, how AMR impacted his life, and thoughts on optimal care delivery.

Credit Expired

Target Audience

This activity is intended for clinicians actively engaged in managing AMR in transplant patients, including transplant physicians, surgeons, NPs, and PAs with an interest in transplant. The goal of this activity is to provide education about AMR treatment principles, guidelines, and emerging therapies. Faculty will discuss the genesis of alloantibody production and how it contributes to graft loss, as well as unmet needs in AMR therapies. An experienced patient with AMR provides insights for transplant clinicians to consider when treating their patients with AMR.

Educational Objectives

Upon completion of this activity, participants should be better able to:

Summarize the pathophysiology of antibody-mediated rejection (AMR), including the role of the complement system and cytokine pathways in disease pathogenesis
Evaluate the efficacy and safety data supporting existing and emerging treatment options for AMR, including anti-complement and anti-cytokine strategies
Select appropriate treatments for patients with AMR to improve allograft survival

Activity Faculty

Robert A. Montgomery, MD, DPhil, FACS (Chair)

Professor, Surgery
Director, NYU Langone Transplant Institute
New York, NY

Arjang Djamali, MD, MS, FASN

Professor, Medicine and Surgery
Head, Division of Nephrology
Department of Medicine
University of Wisconsin
School of Medicine and Public Health
Madison, WI

Stanley C. Jordan, MD, FASN, FAST

Director, Nephrology & Transplant Immunology
Medical Director, Kidney Transplant Program
Cedars-Sinai Medical Center
Professor, Pediatrics & Medicine
David Geffen School of Medicine at UCLA
Los Angeles, CA

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