Although over 100,000 renal transplants are performed worldwide each year, only a fraction of recipients are living with functioning renal grafts. Approximately 40% of renal transplants fail within 10 years. Chronic, or late, renal graft rejection is a leading cause of failure. Management of chronic active antibody-mediated rejection (AMR) is a major challenge due to the lack of both approved treatment options and clinical evidence informing current guidelines. In this fast-paced, highly interactive activity, Drs. Jordan, Djamali, and Schinstock will take you through the pathophysiology, diagnosis, and emerging therapeutics for chronic active AMR.
Upon completion of this activity, participants should be better able to:
Director, Nephrology & Transplant Immunology
Medical Director, Kidney Transplant Program
Cedars-Sinai Medical Center
Los Angeles, CA
Chair, Department of Medicine
Maine Medical Center
Division of Nephrology and Hypertension
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
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