Antibody-Mediated Rejection in Renal Transplantation: Immune Mechanisms, Diagnostic Criteria, & Therapeutic Advances: A Clinical Olympics℠

Activity Overview

Although over 100,000 renal transplants are performed worldwide each year, only a fraction of recipients are living with functioning renal grafts. Approximately 40% of renal transplants fail within 10 years. Chronic, or late, renal graft rejection is a leading cause of failure. Management of chronic active antibody-mediated rejection (AMR) is a major challenge due to the lack of both approved treatment options and clinical evidence informing current guidelines. In this fast-paced, highly interactive activity, Drs. Jordan, Djamali, and Schinstock will take you through the pathophysiology, diagnosis, and emerging therapeutics for chronic active AMR.

0.75 CE Credit(s)
Expires: August 9, 2023

Target Audience

This activity is intended for transplant, nephrology, general surgery, and internal medicine clinicians managing transplant patients with antibody-mediated rejection (AMR).

Learning Objectives

Upon successful completion of this education activity, participants should be better able to:

  • Identify the pathophysiology of chronic active antibody-mediated rejection (AMR) that leads to deleterious clinical manifestations in kidney transplant patients
  • Apply Banff diagnostic criteria for chronic active AMR in renal allografts
  • Examine the potential role of emerging therapeutic approaches in the management of chronic active AMR

Activity Faculty

Jordan

Stanley C. Jordan, MD, FASN, FAST

Director, Nephrology & Transplant Immunology
Medical Director, Kidney Transplant Program
Cedars-Sinai Medical Center
Los Angeles, CA

Djamali_Arjang@2x

Arjang Djamali, MD

Chair, Department of Medicine
Maine Medical Center
Portland, ME

Schinstock_Carrie@2x

Carrie A. Schinstock, MD

Associate Professor
Division of Nephrology and Hypertension
Mayo Clinic
Rochester, MN

Provider Statement

This activity is provided by RMEI Medical Education, LLC

Supporter Statement

This activity is supported by an independent educational grant from CSL Behring LLC.

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