Clinical Reflections®: Reflecting on Missed Opportunities in Nontuberculous Mycobacteria Lung Disease

Program Overview

Nontuberculous mycobacteria lung disease (NTM-LD) is a relatively uncommon condition, although its prevalence is rising. In this interactive CME activity, Drs. Anne O’Donnell and Patrick Flume review 2 patient cases to demonstrate how clinicians can maintain a greater index of suspicion for the diagnosis of NTM-LD to enable timely and effective therapy. The management of NTM-LD remains challenging, owing to the need for long-term treatment, the potential for drug-related toxicities and patient nonadherence. These factors underscore the importance of specialty referral for the successful management of NTM-LD.

Credit Expired

Target Audience

The target audience for this activity is US-based pulmonologists and infectious disease specialists.

Educational Objectives

Upon completion of this activity, participants should be better able to:

  • Describe the current epidemiologic trends and burdens posed by nontuberculous mycobacteria lung disease (NTM-LD) and its treatment
  • Implement recommended diagnostic practices for NTM-LD based on the identification of at-risk patients
  • Institute best practices for NTM-LD management with available treatment options, including proactive monitoring for adverse events and adherence to existing and new treatments

Activity Faculty


Anne E. O'Donnell, MD

Professor, Medicine
Nehemiah and Naomi Cohen Chair, Pulmonary Disease Research
Chief, Division of Pulmonary, Critical Care and Sleep Medicine
Georgetown University Hospital
Washington, DC


Patrick A. Flume, MD

Professor, Medicine and Pediatrics
Powers Huggins Endowed Chair, Cystic Fibrosis
Medical University of South Carolina
Charleston, SC


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