Clinical Reflections®: Ensuring Best Practices in Spinal Muscular Atrophy Management

Program Overview

In this activity, a panel of experts in spinal muscular atrophy (SMA) use a series of case vignettes and clinical reflection points to emphasize the importance of early diagnosis and treatment of patients with pre-symptomatic, infantile-onset, and late-onset SMA.

Credit Expired

Target Audience

Neurology clinicians who diagnose and manage spinal muscular atrophy (SMA) in patients.

Educational Objectives

Upon completion of this activity, participants should be better able to:

  • Describe the expected impact of newborn screening on the early commencement of treatment in patients with spinal muscular atrophy (SMA)
  • Employ available efficacy, safety, and tolerability data on disease-modifying treatments in pre-symptomatic and symptomatic patients with SMA
  • Apply established symptomatic and supportive care strategies in patients with SMA throughout the course of their disease


Activity Faculty

Dr. Castro Headshot

Diana P. Castro, MD (Chair)

Associate Professor, Pediatrics and Neurology
University of Texas Southwestern
Children’s Health
Dallas, TX


John Brandsema, MD

Child Neurologist and Neuromuscular Section Head
Children’s Hospital of Philadelphia
Assistant Professor, Clinical Neurology
Perelman School of Medicine at the University of Pennsylvania
Philadelphia, PA

Headshot Crystal Proud

Crystal M. Proud, MD

Neuromuscular Neurologist  
Children’s Hospital of The King’s Daughters
Norfolk, VA


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