Clinical Reflections®: Ensuring Best Practices in Spinal Muscular Atrophy Management

Program Overview

In this activity, a panel of experts in spinal muscular atrophy (SMA) use a series of case vignettes and clinical reflection points to emphasize the importance of early diagnosis and treatment of patients with pre-symptomatic, infantile-onset, and late-onset SMA.

Credit Expired
0.50 CE Credit(s)
Expires: January 5, 2022

Target Audience

Neurology clinicians who diagnose and manage spinal muscular atrophy (SMA) in patients.

Educational Objectives

Upon completion of this activity, participants should be better able to:

  • Describe the expected impact of newborn screening on the early commencement of treatment in patients with spinal muscular atrophy (SMA)
  • Employ available efficacy, safety, and tolerability data on disease-modifying treatments in pre-symptomatic and symptomatic patients with SMA
  • Apply established symptomatic and supportive care strategies in patients with SMA throughout the course of their disease


Activity Faculty

Dr. Castro Headshot

Diana P. Castro, MD (Chair)

Associate Professor, Pediatrics and Neurology
University of Texas Southwestern
Children’s Health
Dallas, TX


John Brandsema, MD

Child Neurologist and Neuromuscular Section Head
Children’s Hospital of Philadelphia
Assistant Professor, Clinical Neurology
Perelman School of Medicine at the University of Pennsylvania
Philadelphia, PA

Headshot Crystal Proud

Crystal M. Proud, MD

Neuromuscular Neurologist  
Children’s Hospital of The King’s Daughters
Norfolk, VA

Supporter Statement

Provider Statement

Disclosure of Financial Relationships


Planners and Managers

Method of Participation and Request for Credit

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. 

Disclaimer Statement

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. 

Copyright Statement

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