Experts in the Hot Seat: Targeting the Cytokine Pathway in RA Management

Program Overview

During this Experts in the Hot Seat interactive slide-audio activity, we discuss as a panel rheumatoid arthritis and management of patients with this disease. We will address the pathophysiology of rheumatoid arthritis (RA) and targeting cytokine-driven inflammatory responses for therapy, the role of biologic agents targeting cytokines including interleukin-6 (IL-6), debate key issues and challenge one another to dispense complex information in an interesting and easily comprehensible way, while also challenging your knowledge and providing peer benchmarking. This activity also includes discussion of relevant data surrounding evolving guidelines for management of patients with RA and clinical trials of new and emerging targeted biologic therapies.

Credit Expired
CE Credit Expired

Target Audience

The target audience for this activity is physicians, nurse practitioners, and physician assistants who specialize in rheumatology and internal medicine.

Educational Objectives

Upon completion of this activity, participants should be better able to:

  • Delineate the role of TNF and IL-6 signaling pathways in the pathophysiology of rheumatoid arthritis (RA) and the rationale for anti-cytokine therapy as a treatment approach
  • Integrate current standards for disease activity monitoring into informing appropriate management for patients with RA
  • Incorporate emerging clinical trial data regarding the safety and efficacy of novel IL-6 targeting agents for RA into treatment decisions

Activity Faculty

Peter C. Taylor, MA, BM, BCh, PhD, FRCP, FRCPE

Peter C. Taylor, MA, BM, BCh, PhD, FRCP, FRCPE

Norman Collisson Professor, Musculoskeletal Sciences
Oxford University
Director, Clinical Sciences
Botnar Research Centre
Oxford, England

Thomas Dörner, MD, PhD

Thomas Dörner, MD, PhD

Professor, Rheumatology and Clinical Immunology
Charite University Hospitals Berlin and DRFZ Berlin
Berlin, Germany

Juan J. Gómez-Reino, MD, PhD

Juan Gómez-Reino, MD, PhD

Professor, Medicine
Fundación Ramón Dominguez
Hospital Clinico Universitario
Santiago, Spain

Supporter Statement

Provider Statement

Disclosure of Financial Relationships


Planners and Managers

Method of Participation and Request for Credit

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. 

Disclaimer Statement

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. 

Copyright Statement

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