Medical News, Journals & Upcoming Events
Most Read Psychiatry Articles on JAMA Network
- Removing the Reliability Bottleneck in Functional Magnetic Resonance Imaging Research to Achieve Clinical Utility January 13, 2021This Viewpoint enumerates current issues with the reliability and applicability of functional magnetic resonance imaging research and describes options for increasing research utility.
- Depression Risk of Polygenic Liability, Parental Psychiatric History, and Socioeconomic Status January 13, 2021This case-cohort study assesses the individual and joint associations of polygenic risk scores, parental history, and socioeconomic status with relative and absolute risks of early-onset depression.
- Association of Childhood Insulin Levels and Body Mass Index With Mental Health Risks in Young Adults January 13, 2021This cohort study examines changes in fasting insulin levels and body mass index from childhood to age 24 years and the risk for psychiatric disorders in that cohort at age 24 years.
- Identification of Suicide Attempt Risk Factors in a National US Survey Using Machine Learning January 6, 2021This study evaluates future suicide attempt risk factors in the general population using a data-driven machine learning approach that includes more than 2500 questions from a large, nationally representative survey of US adults.
- Efficacy of Yoga vs Cognitive Behavioral Therapy vs Stress Education for Generalized Anxiety Disorder January 1, 2021This randomized clinical trial compares the efficacy of yoga vs a psychological control condition vs cognitive behavior therapy for the management of generalized anxiety disorder.
JAMA Oncology Current Issue
- Systemic Therapy and Sequencing Options in Advanced Hepatocellular Carcinoma December 10, 2020This systematic review with meta-analysis compares the effectiveness of different vascular endothelial growth factor inhibitors, checkpoint inhibitors, or their combinations in patients with advanced hepatocellular carcinoma in the first-line or refractory settings.
- Effect of Machine Learning Mortality Estimates With Behavioral Nudges to Clinicians on Serious Illness Conversations December 10, 2020This stepped-wedge cluster randomized clinical trial assesses the effect of a clinician-directed intervention combining machine learning mortality predictions with behavioral nudges vs usual care on motivating serious illness conversations between clinicians and patients with cancer.
- Appropriate Analysis of Duration of Response Data in Cancer Trials—Reply December 1, 2020In Reply McCaw et al raise important considerations on duration of response (DOR) reporting in clinical trials. Achievement of an objective radiographic response (ORR) as measured by reduction in size of a contrast-enhancing lesion is thought to represent a bona fide parameter of therapeutic benefit associated with cytotoxic agents or immunotherapy for patients with solid […]
- Association of Measurable Residual Disease With Survival in Patients With Acute Myeloid Leukemia December 1, 2020This meta-analysis examines the use of measurable residual disease as an end point in studies to assess survival outcomes in patients with acute myeloid leukemia.
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The New England Journal of Medicine | Primary Care/Hospitalist/Clinical Practice
- Incarceration and Social Death — Restoring Humanity in the Clinical Encounter January 21, 2021Mr. S. a 28-year-old Black man, arrived at our emergency department (ED) by ambulance after exhibiting altered mental status and agitation in jail. While in solitary confinement for 4 days, he repeatedly and unsuccessfully sought the attention of the medical staff. He was brought to the ED after…
- Pelvic Splenosis January 21, 2021Figure 1.
- Vaccinating Children against Covid-19 — The Lessons of Measles January 20, 2021Imagine a highly contagious virus circulating in the community. Many infected children have fever and some general misery but recover without incident. Rarely, devastating complications occur, leading to hospitalization, severe illness, and occasional deaths. Susceptible adults fare worse, with…
- Who Goes First? Government Leaders and Prioritization of SARS-CoV-2 Vaccines January 20, 2021The vice president, Senate majority leader, House speaker, surgeon general, and members of Congress were among the first people vaccinated against Covid-19 in the United States. The president-elect, incoming first lady, vice president-elect, and her husband were also vaccinated in the first phase.…
- Beyond Tuskegee — Vaccine Distrust and Everyday Racism January 20, 2021J. Marion Sims. Henrietta Lacks. The Tuskegee Syphilis Study. With two authorized SARS-CoV-2 vaccines now available, particular concerns have emerged regarding whether Black communities will choose to be vaccinated. In a pandemic that has disproportionately burdened Black Americans, experts have…
The New England Journal of Medicine Rheumatology
- Osteoarthritis of the Knee January 7, 2021Foreword. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author’s clinical recommendations. Stage. A 60-year-old…
- Microvascular Injury in the Brains of Patients with Covid-19 December 30, 2020To the Editor: We conducted postmortem high-resolution magnetic resonance imaging (magnetic resonance microscopy) of the brains of patients with coronavirus disease 2019 (Covid-19) (median age, 50 years) and histopathological examination that focused on microvascular changes in the olfactory bulb…
- Case 39-2020: A 29-Month-Old Boy with Seizure and Hypocalcemia December 17, 2020Presentation of Case. Dr. Neil D. Fernandes: A 29-month-old boy was transferred to this hospital because of a seizure and hypocalcemia. Approximately 2 months before the current evaluation, the patient had a febrile seizure associated with an acute viral illness. After the seizure, his mother…
- Covid-19–Associated Myopathy Caused by Type I Interferonopathy December 10, 2020To the Editor: The syndrome of Covid-19 infection includes myalgias and elevated creatine kinase levels in at least a third of patients. Whether the elevation in creatine kinase level is caused by viral infection of muscle, toxic effects of cytokines, or another mechanism is unclear. There are few…
