Medical News, Journals & Upcoming Events
Most Read Psychiatry Articles on JAMA Network
- Use of the PsycheMERGE Network to Investigate Depression Scores and White Blood Cell Count December 1, 2021This genetic association study uses data from Vanderbilt University Medical Center and the PsycheMERGE network to investigate the association between inflammatory biomarkers, such as white blood cell count, and the genes that predispose an individual to depression.
- Perturbations in Gut Microbiota Composition in Psychiatric Disorders December 1, 2021This systematic review and meta-analysis reviews gut microbiota alterations in general adult psychiatric populations and performs a within- and between-diagnostic comparison.
- Prevention of Incident and Recurrent Major Depression in Older Adults With Insomnia November 24, 2021This randomized clinical trial of adults without depression but with insomnia assesses whether insomnia treatment can prevent depression.
- Lithium for Suicide-Related Outcome Prevention in Veterans With Major Depression or Bipolar Disorder November 17, 2021This randomized clinical trial assesses whether the addition of lithium to existing medication regimens would prevent or delay repeated suicide-related events and whether it could be used safely.
- Association of Single-Blind Placebo Run-in Periods With the Placebo Response in Antidepressant RCTs November 10, 2021This meta-analysis of 347 trials examines the association of the use of placebo run-in periods with the placebo response, drug response, and drug-placebo difference among randomized clinical trials of antidepressants.
JAMA Oncology Current Issue
- Geriatric Assessment–Driven Intervention and Chemotherapy Toxic Effects in Older Adults With Cancer November 18, 2021This randomized clinical trial assesses whether geriatric assessment–driven intervention can reduce chemotherapy-related toxic effects in older adults with cancer.
- Reduced-Intensity Chemotherapy for Advanced Gastroesophageal Cancer in an Older Population November 1, 2021To the Editor In their randomized clinical trial among older and frail patients with advanced gastroesophageal cancer, Hall and colleagues compared 3 dosing strategies: oxaliplatin/capecitabine at Level A (oxaliplatin 130 mg/m2 on day 1, capecitabine 625 mg/m2 twice daily on days 1-21, on a 21-day cycle), Level B (doses 0.8 times A), and Level C […]
- Unilateral Leg Swelling in a Young Woman November 1, 2021A 33-year-old woman with a history of hereditary bilateral retinoblastoma as an infant presents with 1 week of right lower extremity swelling. What is your diagnosis?
- Neoadjuvant Endocrine Therapy in Clinical Practice November 1, 2021This review summarizes clinical aspects related to the application of neoadjuvant endocrine therapy in the treatment of hormone receptor–positive/ERBB2-negative breast cancer.
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The New England Journal of Medicine | Primary Care/Hospitalist/Clinical Practice
- New Creatinine- and Cystatin C–Based Equations to Estimate GFR without Race November 4, 2021The glomerular filtration rate (GFR) is generally estimated from serum concentrations of endogenous filtration markers such as creatinine or cystatin C. During the past two decades, automated clinical laboratory reporting of GFR estimated with the use of creatinine (eGFRcr) has become widespread,…
- Time to Eliminate Health Care Disparities in the Estimation of Kidney Function November 4, 2021In the wake of the racial reckoning since the spring of 2020 in the United States, efforts have emerged to identify hidden structural determinants of systemic racism in medicine. Such efforts have led to examination of traditional medical algorithms that incorporate race modifiers and may have led…
- Disseminated Cryptococcosis October 28, 2021Figure 1.
- Case 33-2021: A 68-Year-Old Man with Painful Mouth Ulcers October 28, 2021Presentation of Case. Dr. Ian D. Cooley (Medicine): A 68-year-old man was admitted to this hospital because of painful mouth ulcers and weight loss. The patient had been well until 6 weeks before the current admission, when painful mouth ulcers and neck pain developed. He was evaluated at an urgent…
- Management of Abdominal Aortic Aneurysms October 28, 2021Foreword. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors’ clinical recommendations. Stage. A 64-year-old…
The New England Journal of Medicine Rheumatology
- Case 33-2021: A 68-Year-Old Man with Painful Mouth Ulcers October 28, 2021Presentation of Case. Dr. Ian D. Cooley (Medicine): A 68-year-old man was admitted to this hospital because of painful mouth ulcers and weight loss. The patient had been well until 6 weeks before the current admission, when painful mouth ulcers and neck pain developed. He was evaluated at an urgent…
- Case 30-2021: A 47-Year-Old Man with Recurrent Unilateral Head and Neck Pain September 30, 2021Presentation of Case. Dr. David M. Dudzinski: A 47-year-old right-handed man was evaluated at this hospital because of pain on the left side of the head and neck. Six years before the current evaluation, the patient was admitted to this hospital with 1 week of headache, pain on the left side of the…
- Case 29-2021: A 12-Month-Old Boy with Fever and Developmental Regression September 23, 2021Presentation of Case. Dr. Emma C. Materne (Pediatrics): A 12-month-old boy with Hirschsprung’s disease was admitted to this hospital because of fever. Fifteen days before the current admission, the patient had a temperature of 39.7°C. His parents noticed that he was fussy and less active than usual…
- Reframing Immune-Mediated Inflammatory Diseases through Signature Cytokine Hubs August 12, 2021Immune-mediated inflammatory diseases (IMIDs) are a heterogeneous group of diseases characterized by chronic inflammation and organ damage. IMIDs were traditionally classified on the basis of the predominant organ involvement. Improving the pathogenic characterization of IMIDs, however, should…
