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RSS The New England Journal of Medicine | Primary Care/Hospitalist/Clinical Practice
RSS The New England Journal of Medicine Rheumatology
  • Case 29-2021: A 12-Month-Old Boy with Fever and Developmental Regression September 23, 2021
    Presentation of Case. Dr. Emma C. Materne (Pediatrics): A 12-month-old boy with Hirschsprung’s disease was admitted to this hospital because of fever. Fifteen days before the current admission, the patient had a temperature of 39.7°C. His parents noticed that he was fussy and less active than usual…
  • Reframing Immune-Mediated Inflammatory Diseases through Signature Cytokine Hubs August 12, 2021
    Immune-mediated inflammatory diseases (IMIDs) are a heterogeneous group of diseases characterized by chronic inflammation and organ damage. IMIDs were traditionally classified on the basis of the predominant organ involvement. Improving the pathogenic characterization of IMIDs, however, should…
  • CD19-Targeted CAR T Cells in Refractory Systemic Lupus Erythematosus August 5, 2021
    To the Editor: Systemic lupus erythematosus (SLE) is a severe autoimmune disease that predominantly affects young women. SLE is characterized by the formation of autoantibodies and immune complex–mediated inflammation and organ damage. Although autoreactive B cells play a key role in the…
  • Decompression with or without Fusion in Degenerative Lumbar Spondylolisthesis August 5, 2021
    Degenerative spondylolisthesis is a condition in which one vertebra has slipped forward in relation to the next lower vertebra. Patients, usually older than 60 years of age, typically have leg and back pain and restricted function due to lumbar spinal stenosis caused by spondylolisthesis, disc…

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