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  • Lymphoma With a Skin Rash August 1, 2024
    A 62-year-old female had a generalized vesiculobullous rash on her face for 4 months. It started over the lips and gradually progressed to involve the oral mucosa and skin of the whole body. What is your diagnosis?
  • Immunotherapy For US Patients With Metastatic Cancer at the End of Life—Reply August 1, 2024
    In Reply We agree with Higashi et al that studies including performance status, quality-of-life metrics, and specific immunotherapy agents used at the end of life would provide additional helpful insights into the trends reported in our study. We regret that these data are not available in the National Cancer Database. In regard to the comment […]
  • Valid Analysis of Brain-Specific Progression-Free Survival August 1, 2024
    Chen and colleagues conducted a clinical trial to investigate whether the addition of an induction treatment of bevacizumab, etoposide, and cisplatin (BEEP) would improve brain-specific progression-free survival (PFS) after whole-brain radiotherapy. The primary end point was brain PFS as assessed by local investigators. The study was designed to detect a hazard ratio of 0.6 with […]
  • Valid Analysis of Brain-Specific Progression-Free Survival—Reply August 1, 2024
    In Reply We appreciate Armbruster et al and Yu et al for their interest and comments regarding our A-PLUS study.

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