Exploiting BCMA in the Treatment of Multiple Myeloma: How Could Bispecific Antibodies and T-Cell Engagement Impact Relapsed/Refractory Disease? Proceedings from a Clinical Olympics℠

Program Overview

The advent of BCMA-directed therapy fills a significant gap in the treatment of relapsed/refractory multiple myeloma. As the field rapidly evolves, clinicians are challenged to navigate an increasingly complex therapeutic landscape. In this clinically relevant, high-level activity, Dr. Sundar Jagganath, Dr. María-Victoria Mateos, and Dr. James Hoffman provide privileged insights into optimal selection and integration of BCMA-directed therapies, particularly bispecific antibodies, to maximize patient outcomes.

Credit Expired
1.0 CE Credit(s)
Expires: January 29, 2024

Target Audience

Medical oncologists, hematologists, hematologist-oncologists, pathologists, and oncology nurses

Educational Objectives

Upon completion of this activity, participants should be better able to:

  • Select an appropriate B cell maturation antigen (BCMA) targeted therapy among approved options for patients with relapsed/refractory (R/R) multiple myeloma (MM)
  • Integrate novel BCMA-targeted therapies into the treatment paradigm of R/R MM, with an emphasis on bispecific antibodies
  • Manage adverse events (AEs) associated with BCMA-directed therapies in patients with R/R MM

Activity Faculty

908-JagannathS

Sundar Jagannath, MD, FASCO

Chair, Multiple Myeloma
Professor, Medicine
Icahn School of Medicine at Mount Sinai
Director, Multiple Myeloma Center of Excellence
Tisch Cancer Center Institute
Editor-in-Chief, Clinical Lymphoma, Myeloma & Leukemia
Mount Sinai Hospital
New York, NY

908-HoffmanJ

James Hoffman, MD

Associate Professor, Clinical Medicine
Division of Myeloma (Hematology)
Sylvester Comprehensive Cancer Center (SCCC)
University of Miami
Miami, FL

908-MateosM

María-Victoria Mateos, MD, PhD

Associate Professor, Hematology
Director, Myeloma Program
University Hospital of Salamanca
Salamanca, Spain

Supporter Statement

Provider Statement

Disclosure of Financial Relationships

Faculty

Planners and Managers

Provider Statement 

Provided by RMEI Medical Education, LLC 

Statement of Commercial Support 

This activity is supported by an independent medical education grant from Regeneron Pharmaceuticals, Inc. 

Disclosure of Financial Relationships 

RMEI Medical Education, LLC (RMEI) requires instructors, planners, managers, and others in control of educational content to disclose all their financial relationships with ineligible companies over the previous 24 months. All identified financial relationships are thoroughly vetted and mitigated according to RMEI policy. 

Faculty 

James Hoffman, MD, has relevant financial relationships with Bristol Myers Squibb (Speaker/Speaker’s Bureau). 

Sundar Jagannath, MD, FASCO, has relevant financial relationships with Epizyme, Karyopharm Therapeutics (Advisor); Bristol Myers Squibb, Genentech, Janssen Pharmaceuticals, Legend Biotech, Sanofi (Consultant). 

María-Victoria Mateos, MD, PhD, has relevant financial relationships with Amgen, Bristol Myers Squibb, GSK, Janssen Pharmaceuticals, Oncopeptides, Inc., Pfizer, Sanofi, Seagen, Inc. (Advisor); Amgen, Bristol Myers Squibb, GSK, Janssen Pharmaceuticals, Pfizer, Sanofi, Takeda (Speaker/Speaker’s Bureau). 

All of the relevant financial relationships listed for these individuals have been mitigated according to RMEI policies. 

Planners and Managers 
RMEI Medical Education, LLC planners and managers have no relevant financial relationship(s) with ineligible companies to disclose with the exception of Sara Fagerlie, PhD, CHCP, medical writer, who had a relevant financial relationship with Adaptive Biotechnologies (Consultant). This relevant financial relationship has been divested. 

Accreditation Statement 

In support of improving patient care, RMEI Medical Education, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

 

 

Designation of Credit 

Physician Continuing Medical Education 
RMEI Medical Education, LLC designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

Continuing Nursing Education 
The maximum number of hours awarded for this Continuing Nursing Education activity is 1.0 contact hour(s). 

Instructions for Receiving Credit 

In order to receive credit, participants must review the activity content and successfully complete both the post-test and evaluation. A statement of credit will be available to print immediately. You must score 80% or higher on the post-test to receive credit for this activity. If you have questions about this activity, please contact RMEI at [email protected]. 

Users must: 

  • Read the learning objectives and faculty disclosures 
  • Participate in the activity 
  • Complete the activity evaluation and attest to credit

 

There is no fee to participate. 

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Disclosure of Unlabeled Use 

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. 

Disclaimer Statement 

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. 

Resources 

Method of Participation and Request for Credit

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. 

Disclaimer Statement

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. 

Copyright Statement

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