Acute myeloid leukemia (AML), the most common form of leukemia, is characterized by a wide range of cytogenetic and molecular aberrations. These aberrations determine risk classification and, if available, targeted therapy. Recent data has changed the diagnostic threshold for AML, as well as risk classification and data on emerging therapies, by reshaping the future of treatment for newly diagnosed and relapsed/refractory AML. Join Drs. Amer Zeidan and Kendra Sweet as they discuss these and other recent updates in AML.
Upon completion of this activity, participants should be better able to:
Associate Professor, Medicine (Hematology)
Yale Cancer Center
Yale University
New Haven, CT
Associate Member, Malignant Hematology Faculty
Medical Director, Clinical Research
Department of Malignant Hematology
H. Lee Moffitt Cancer Center
Tampa, FL
Resources
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Kendra Sweet, MD, MS, has relevant financial relationships with Astellas Pharma, Inc., BerGenBio, Bristol Myers Squibb, Curis, Inc., Gilead, Jazz Pharmaceuticals, MABLYTICS, Inc., Novartis (Consultant); AROG Pharmaceuticals, Inc., ImmunoGen, Inc., Incyte Corporation, Jazz Pharmaceuticals, Loxo Oncology, Inc., MacroGenics, Minneamrita Therapeutics LLC, StemlineTherapeutics Inc. (Grant/Research Support).
Amer Zeidan, MBBS, MHS, has relevant financial relationships with AbbVie, Acceleron Pharma Inc., Agios Pharmaceuticals, ALX Oncology, Amgen, Aprea Therapeutics, Astellas Pharma, Inc., BeyondSpring Pharma, BioCryst Pharmaceuticals, Boehringer-Ingelheim, Bristol Myers Squibb, Cardiff Oncology, Cardinal Health, Celgene, Chiesi USA, Inc., Daiichi Sankyo, Epizyme, Inc., Foran, Genentech, Geron Corporation, Gilead, Incyte Corporation, Ionis Pharmaceuticals, Inc., Janssen Pharmaceuticals, Jazz Pharmaceuticals, Kura, Mendus, Notable Labs, Novartis, Orum, Otsuka Pharmaceutical Co., Ltd, Pfizer, Seattle Genetics, Servier, Syndax Pharmaceuticals Inc., Syros Pharmaceuticals, Inc., Taiho Pharmaceutical, Takeda, TrovaGene, Inc., Tyme (Consultant); AbbVie, ADC Therapeutics, Amgen, Aprea Therapeutics, Astex, AstraZeneca, Boehringer-Ingelheim, Bristol Myers Squibb, Cardiff Oncology, Celgene, Geron Corporation, Incyte Corporation, MedImmune, Novartis, Otsuka Pharmaceutical Co., Ltd, Pfizer, Shattuck Labs, Takeda, TrovaGene, Inc. (Grant/Research Support); AbbVie, ALX Oncology, BioCryst Pharmaceuticals, Bristol Myers Squibb, Celgene, Geron Corporation, Gilead, Kura, Novartis, Syros Pharmaceuticals, Inc. (Other: Clinical Trial Committees); AbbVie, Acceleron Pharma Inc., Agios Pharmaceuticals, ALX Oncology, Amgen, Aprea Therapeutics, Astellas Pharma, Inc., BeyondSpring Pharma, BioCryst Pharmaceuticals, Boehringer-Ingelheim, Bristol Myers Squibb, Cardiff Oncology, Cardinal Health, Celgene, Chiesi USA, Inc., Daiichi Sankyo, Epizyme, Inc., Foran, Genentech, Geron Corporation, Gilead, Incyte Corporation, Ionis Pharmaceuticals, Inc., Janssen Pharmaceuticals, Jazz Pharmaceuticals, Kura, Mendus, Notable Labs, Novartis, Orum, Otsuka Pharmaceutical Co., Ltd, Pfizer, Seattle Genetics, Servier, Syndax Pharmaceuticals Inc., Syros Pharmaceuticals, Inc., Taiho Pharmaceutical, Takeda, TrovaGene, Inc., Tyme (Other: Honorarium); Cardiff Oncology, Novartis, Pfizer (Other: Travel Support).
All of the relevant financial relationships listed for these individuals have been mitigated according to RMEI policies.
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This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
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