Navigating the Frontier of Hematologic Malignancy Therapies. Series of 5 Modules

Program Overview

This activity will cover the latest advances in the therapeutic management of hematologic malignancies, including bispecific antibodies, CAR-T products, proteolysis-targeting chimeras, and antibody-drug conjugates — with an emphasis on novel targets and approaches. The prognostic role of circulating tumor DNA is also explored.

Credit Expired

Target Audience

Hematologists, oncologists, and other healthcare professionals involved in the diagnosis and treatment of patients with blood cancers.

Educational Objectives

Upon completion of this activity, participants should be better able to:

Analyze available data on bispecific antibodies for the treatment of multiple myeloma (Module 1 CME 0.5 credit)
Identify potential T-cell immunotherapeutic strategies for the treatment of lymphomas and other hematologic malignancies (Module 2 CME 0.5 credits)
Describe emerging proteolysis targeting chimeras (PROTACs) under investigation for the treatment of hematologic malignancies (Module 3 CME 0.5 credits)
Assess key data sets and ongoing clinical trials investigating antibody-drug conjugates for the treatment of acute myeloid leukemia (AML) (Module 4 CME: 0.5 credits)
Examine the potential utility of circulating tumor DNA for risk prediction and individualizing therapy for diffuse large B-cell lymphoma (DLBCL) (Module 5 CME: 1.0 credit)

Activity Faculty

Helen E. Heslop, MD, DSc (Hon) (Chair)

Professor, Departments of Medicine and Pediatrics
Director, Center for Cell and Gene Therapy
Dan L. Duncan Chair
Interim Director, Dan L. Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, TX

Saad Z. Usmani, MD, MBA, FACP

Chief, Myeloma Service
Memorial Sloan Kettering Cancer Center
New York, NY

Katherine Donovan, PhD

Lead Scientist, Department of Cancer Biology
Dana-Farber Cancer Institute
Harvard Medical School
Boston, MA

Soheil Meshinchi, MD, PhD

Full Member, Fred Hutchinson Cancer Center
Professor, Pediatrics
University of Washington
Seattle, WA

Mark Roschewski, MD

Clinical Director, Lymphoid Malignancies Branch
Center for Cancer Research
National Cancer Institute, NIH
Bethesda, MD

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