Latest Pulmonology Articles

• Continuous or Intermittent Renal-Replacement Therapy — What Is the Question? October 29, 2026
  Acute kidney injury is a common complication in critically ill patients and is associated with substantial morbidity and mortality. In the absence of effective pharmacotherapy, care is primarily supportive, with reliance on renal-replacement therapy until kidney function recovers. Although more than eight decades have passed since Willem Kolff performed the...
  Paul M. Palevsky
• Tozorakimab to Prevent COPD Exacerbations October 29, 2026
  In two replicate phase 3 trials involving patients with COPD who were receiving inhaled maintenance therapy, add-on tozorakimab resulted in a lower rate of moderate or severe exacerbations than placebo.
  Frank C. Sciurba, Henrik Watz, Arnaud Bourdin, Wim Janssens, Fernando J. Martinez, Jinping Zheng, Maarten van den Berge, Matteo Bonini, MeiLan K. Han, Dave Singh, Gerard J. Criner, Christopher E. Brightling, Alberto Papi, Surya P. Bhatt, Martin Jenkins, Marta Mikosz, Piotr Chołbiński, Monika Ziemiecka, Magnus Löfdahl, Deepa Arya, Madhavi Yadavalli, Bryan H. Brodek, Malin Fagerås, Samuel Bardsley, Neil Martin, Rajesh Patel, Ioannis Psallidas, the OBERON and TITANIA Trial Investigators*
• Intermittent or Continuous Renal-Replacement Therapy in Acute Kidney Injury October 29, 2026
  An open-label, randomized, noninferiority trial showed that intermittent hemodialysis was not noninferior to continuous renal-replacement therapy in critically ill adults with acute kidney injury.
  Stéphane Gaudry, Marouane Boubaya, Guillaume Louis, Khalil Chaïbi, Etienne de Montmollin, Julien Bohé, Maxime Desgrouas, Clément Devautour, Adrien Joseph, Bruno Mégarbane, Christophe Camus, Pierre Bailly, Alexis Lambour, Romain Arrestier, Samir Jaber, Adrien Robine, Nicolas Chudeau, Guillaume Chevrel, Béatrice La Combe, Jonathan Nicolas, Laurent Argaud, Côme Bureau, Antoine Kimmoun, Noémie Zucman, Jean-Damien Ricard, Guillaume Thiery, Stanislas Faguer, Mathieu Jozwiak, Nathan Ferrand, Benjamin Chousterman, Mehdi Marzouk, Julien Cadiet, Alain Combes, Arnaud Mari, Damien Contou, Roland Amathieu, Daniel Da Silva, Charlotte Salmon Gandonnière, Pierre-André Rodie-Talbere, Isabelle Durand-Zaleski, Patrick Rossignol, Jean-Pierre Quenot, Lucie Biard, Coralie Bloch, Didier Dreyfuss, the ICRAKI Trial Group*