Latest Rheumatology Articles

• Progress through Persistence — Turning the Page in Pulmonary Fibrosis Clinical Trials May 19, 2025
  The field of pulmonary fibrosis has come a long way in the past 25 years, with the approach to patient care evolving from a predominantly experience-based decision-making model to a more data-driven model. Along that journey, we have learned that certain practices that were considered to be standards of care...
  Joyce S. Lee
• Methotrexate as Initial Therapy for Symptomatic Pulmonary Sarcoidosis? May 18, 2025
  Sarcoidosis, a granulomatous disease that affects the lungs and other organs, has a variable course. Although spontaneous resolution of sarcoidosis occurs in some patients, half the patients with sarcoidosis receive glucocorticoid treatment for months to years.1 The need for long-term therapy is usually attributed to high rates of...
  Robert P. Baughman, Elyse E. Lower
• First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate May 18, 2025
  In this randomized trial, first-line treatment of pulmonary sarcoidosis with methotrexate was noninferior to that with prednisone regarding the change at 24 weeks in the percentage of the predicted forced vital capacity.
  Vivienne Kahlmann, Montse Janssen Bonás, Catharina C. Moor, Jan C. Grutters, Rémy L.M. Mostard, Henricus N.A.J. van Rijswijk, Jan van der Maten, Emiel R. Marges, Linda A.A. Moonen, Maria J. Overbeek, Bart Koopman, Daan W. Loth, Esther J. Nossent, Michiel Wagenaar, Henk Kramer, Pascal L.M.L. Wielders, Peter I. Bonta, Stefan Walen, Brigitte A.H.A. Bogaarts, Réne Kerstens, Mayka Overgaauw, Marcel Veltkamp, Marlies S. Wijsenbeek